JAK 3 inhibitor IV

SKU: orb1702969

Description

JAK 3 inhibitor IV (ZM 39923 hydrochloride) is a selective inhibitor of JAK1 and JAK3 with pIC50 values of 4.4 and 7.1, respectively, exhibiting minimal activity against JAK2 and moderate potency against EGFR. It also demonstrates sensitivity to transglutaminase. This compound is utilized in biochemical research to investigate JAK-STAT signaling pathways in cellular and enzymatic assays.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

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Key Properties

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CAS Number	58753-54-1
MW	241.33
Purity	98.00%
Formula	C₁₆H₁₉NO
SMILES	O=C(C1=CC=C2C=CC=CC2=C1)CCNC(C)C
Target	EGFR,Glutaminase,JAK

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

12254523 ↗

Key Properties

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No computed properties available.

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