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JAK-IN-25

SKU: orb2278818

Description

JAK-IN-25 is a potent and selective JAK inhibitor with low nM IC50 values against TYK2, JAK1, and JAK2, and it potently inhibits IL-12 in human whole blood. This profile supports its utility for in vitro and in vivo research in oncology and autoimmune disease models, as indicated in scientific literature.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number2127110-22-7
MW379.37
Purity97.29% (May vary between batches)
FormulaC19H17N5O4
SMILESO=C(OC)C1=NN2C=C(NC(=O)C2=C1)C=3C=NN(C3)CC4=CC=C(OC)C=C4
TargetJAK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 120.00
5 mg
$ 220.00
1 ml x 10 mM (in DMSO)
$ 230.00
10 mg
$ 320.00
25 mg
$ 610.00
50 mg
$ 940.00
100 mg
$ 1,530.00
DispatchUsually dispatched within 5-10 working days
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