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JAK-IN-31

SKU: orb2277595

Description

JAK-IN-31 is a potent pan-JAK inhibitor with IC50 values ≤0.01 µM against JAK1, JAK2, and Tyk2, and 0.01-0.1 µM for JAK3. It is a valuable research tool for investigating JAK/STAT signaling in oncology, supporting both in vitro cellular assays and in vivo preclinical studies in cancer models.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number2597016-88-9
MW465.55
FormulaC21H19N7O2S2
SMILESN(C=1C(=CN=C2C1C=CN2)C=3SC(C)=NN3)[C@@H]4C[C@H](NS(=O)(=O)C5=CC(C#N)=CC=C5)C4
TargetJAK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information