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JAK1-IN-12

SKU: orb2565928

Description

JAK1-IN-12 is a potent and selective JAK1 inhibitor with an IC50 of 24.6 nM, showing significant selectivity over JAK2, JAK3, and TYK2. This compound has demonstrated efficacy in promoting hair growth in mouse models, supporting its use in research for immune, inflammatory, and dermatological conditions.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number2945204-95-3
MW349.43
FormulaC20H23N5O
SMILESN([C@@H]1[C@@]2(CC3(O)C[C@@]1(CC(C2)C3)[H])[H])C=4C(=CN=C5C4C=CN5)C=6C=NNC6
TargetJAK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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JAK1-IN-12 (orb2565928)

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