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JAK1-IN-13

SKU: orb2565927

Description

JAK1-IN-13 (compound 36b) is a potent and highly selective oral JAK1 inhibitor with a 0.044 nM IC50, effectively suppressing STAT3 phosphorylation. It is a valuable research tool for investigating JAK1-dependent pathways in autoimmune and inflammatory disease models, both in vitro and in vivo.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number2778330-90-6
MW445.48
FormulaC23H26F3N5O
SMILESN(C1=C2C(=NC=C1C(NC)=O)NC=C2)[C@@H]3C[C@H](C)N(CC4=CC=C(C(F)(F)F)C=C4)CC3
TargetJAK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information