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JAK1/TYK2-IN-1

SKU: orb1691408

Description

JAK1/TYK2-IN-1 is a potent dual inhibitor targeting both JAK1 and TYK2 kinases with IC50 values of 41 nM and 29 nM, respectively. This compound is a valuable research tool for investigating JAK/STAT signaling pathways in autoimmune and inflammatory disease models, both in cellular and biochemical assays.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number1883300-48-8
MW407.401
FormulaC18H20F3N7O
SMILES[H][C@@]12CN(C[C@]1(NC(=O)[C@@H]1CC1(F)F)[C@@H]2C)c1nc(Nc2cnn(C)c2)ncc1F
TargetJAK,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

JAK1/TYK2-IN-1 (orb1691408)

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