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JAK/HDAC-IN-2

SKU: orb2278465

Description

JAK/HDAC-IN-2 is a dual-targeting 2-amino-4-phenylaminopyrimidine compound that potently inhibits JAK1/2 and HDAC3/6 at nanomolar levels. It induces apoptosis, blocks histone deacetylation and STAT3 phosphorylation, showing robust antiproliferative effects in studies of hematologic cancers and solid tumor models.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

MW570.7
FormulaC28H38N6O5S
TargetHDAC,JAK,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information