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JNJ-9676

SKU: orb2944241

Description

JNJ-9676 is a potent, orally bioavailable small molecule inhibitor targeting the transmembrane domain of the coronavirus membrane (M) protein dimer. By disrupting viral assembly, it demonstrates nanomolar antiviral efficacy against SARS-CoV-2 and SARS-CoV in vitro, supporting its utility as a research tool for studying coronavirus pathogenesis and therapeutic strategies.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology

Images & Validation

Key Properties

CAS Number3026520-19-1
MW497.5
Purity99.83%
FormulaC28H21F2N5O2
SMILESC(NC1=CC(C#N)=CC=C1)(=O)C2=C3N(C[C@H](C)N(C3=O)C4=CC=C(C(F)(F)C5=CC=CC=C5)C=C4)N=C2
TargetDNA/RNA Synthesis,SARS-CoV
SolubilityDMSO:180 mg/mL (361.81 mM);10% DMSO+40% PEG300+5% Tween-80+45% Saline:5 mg/mL (10.05 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

JNJ9676
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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JNJ-9676 (orb2944241)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
¥ 2,470.00
5 mg
¥ 5,330.00
1 ml x 10 mM (in DMSO)
¥ 5,720.00
10 mg
¥ 8,320.00
25 mg
¥ 16,510.00
50 mg
¥ 25,610.00
100 mg
¥ 37,960.00
DispatchUsually dispatched within 5-10 working days
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