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JR14a

SKU: orb1298193

Description

JR14a

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number2411440-41-8
MW533.47
Purity99.29% (May vary between batches)
FormulaC25H26Cl2N4O3S
SMILESCc1cc(sc1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1
TargetComplement System
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.19 mM);DMSO:250 mg/mL (468.63 mM)

Bioactivity

In Vivo
JR14a reduces mast cell degranulation and macrophage infiltration in BR103-induced rat paw edema.
In Vitro
In vitro, thiophene compounds potently inhibited intracellular Ca2+ release in human macrophages without inhibiting the agonist effects in the same concentration range as the related Complement protein C5a.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

JR14a, JR-14a, inhibit, inflammation, Inhibitor, 5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride, C3a, Complement System, ComplementSystem, complement

Similar Products

  • JR14a [orb1218316]

    >98% (HPLC)

    2411440-41-8

    533.47

    C25H26Cl2N4O3S

    5 mg, 10 mg, 100 mg, 25 mg, 50 mg, 1 g, 200 mg, 500 mg
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 130.00
5 mg
$ 240.00
1 ml x 10 mM (in DMSO)
$ 270.00
10 mg
$ 360.00
25 mg
$ 580.00
50 mg
$ 810.00
100 mg
$ 1,120.00
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