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JTV-519 hemifumarate

SKU: orb1709357

Description

JTV-519 hemifumarate is a small molecule exhibiting antiarrhythmic and cardioprotective properties. It functions as a Ca2+-dependent SERCA inhibitor and a partial ryanodine receptor agonist, making it a valuable research tool for studying calcium handling in cardiac muscle in both in vitro and in vivo models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number1435938-25-2
MW965.28
FormulaC54H68N4O8S2
SMILESOC(=O)C=CC(O)=O.COc1ccc2SCCN(Cc2c1)C(=O)CCN1CCC(Cc2ccccc2)CC1.COc1ccc2SCCN(Cc2c1)C(=O)CCN1CCC(Cc2ccccc2)CC1 |w:4.4|
TargetMELK,Calcium Channel

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

JTV-519 hemifumarate (orb1709357)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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