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Description

K11 is a thermally and pH-stable antimicrobial peptide active against multidrug-resistant Klebsiella pneumoniae, with MIC values from 8-512 μg/mL. It disrupts biofilm formation and exhibits synergistic effects with several antibiotics, supporting its investigation for novel anti-infective strategies in both in vitro and in vivo research contexts.

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

TargetAntibacterial
CAS Number1398109-79-9
MW2493.09
FormulaC123H198N32O23
SMILESC([C@@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@@H](CC3=CN=CN3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N)=O)=O)CCCCN)=O)CCCCN)=O)C)=O)CO)=O)=O)CC(C)C)=O)=O)CCCCN)=O)CCCCN)=O)[C@@H](C)O)=O)CC(C)C)=O)CCCCN)=O)CCCCN)=O)[C@H](CC)C)=O)=O)CO)=O)CCCCN)=O)NC([C@H](CCCCN)N)=O)C=5C=6C(NC5)=CC=CC6

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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K11 (orb2277096)

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