KDM1B (N) Antibody, Rabbit Polyclonal

SKU: orb66973

Description

Rabbit polyclonal to KDM1B.Lysine-specific histone demethylase 1B (KDM1B) belongs to the flavin monoamine oxidase family.KDM1B is a histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetictranscriptional activation, thereby acting as a corepressor. KDM1B is required for de novo DNAmethylation of a subset of imprinted genes during oogenesis. KDM1B demethylates both mono-anddi-methylated 'Lys-4' of histone H3, but has no effect on tri-methylated 'Lys-4' or other methylated Lysresidues of histone H3 or H4.

Research Area

Developmental Biology, Epigenetics

Images & Validation

−

Item 1 of 1

Tested Applications	ChIP, IP, WB
Dilution range	WB:1:1000-1:5000
Reactivity	Human

Key Properties

−

Host	Rabbit
Clonality	Polyclonal
Immunogen	N-terminal region of human KDM1B
Molecular Weight	92
Purity	Affinity purification
Conjugation	Unconjugated

Storage & Handling

−

Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives	0.01% NaN3
Disclaimer	For research use only

Alternative Names

−

anti-KDM1B antibody,anti-Lysinespecific histone demethylase 1B antibody,anti-Flavincontaining amine oxidase domaincontaining protein 1 Lysinespecific histone demethylase 2 antibody,anti-AOF1 antibody,anti-C6orf193 antibody,anti-LSD2 antibody

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Western blot analysis of total cell extracts from mouse thymus(Lane1),human HepG2(Lane2) and human Hela(Lane3) using KDM1B antibody

Quick Database Links

UniProt

Q8NB78

UniProt Details

−

No UniProt data available

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Western Blot (IB, immunoblot)

View Protocol

Immunoprecipitation

View Protocol

ChIP

Chromatin Immunoprecipitation

View Protocol

Find More Protocols