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KDM5B (N) Antibody, Rabbit Polyclonal

SKU: orb66907

Description

Rabbit polyclonal to KDM5B.Lysine (K)-specific demethylase 5B (KDM5B) is a ubiquitously expressed nuclear protein. It is ahistone demethylase that specifically demethylates Lys-4 of histone H3. It can demethylatetrimethylated, dimethylated, and monomethylated Lys-4. It acts as a transcriptional corepressor forFOXG1B and PAX9. It favors the proliferation of breast cancer cells by repressing tumor suppressorgenes such as BRAC1 and HOXA5. In contrast, KDM5B may act as a tumor suppressor formelanoma.

Research Area

Metabolism Research

Images & Validation

Tested ApplicationsWB
Dilution RangeWB:1:1000-1:5000
ReactivityHuman, Mouse

Key Properties

HostRabbit
ClonalityPolyclonal
ImmunogenN-terminal region of human KDM5B
Molecular Weight176
PurityAffinity purification
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives0.01% NaN3
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

anti-KDM5B antibody,anti-CT31 antibody,anti-FLJ10538 antibody,anti-FLJ12491 antibody,anti-FLJ16281 antibody,anti-FLJ23670 antibody,anti-JARID1B. PLU1 antibody,anti-PLU1 antibody,anti-PUT1 antibody,anti-RBBP2H1 antibody,anti-Cancer antibody,anti-testis antigen 31 antibody,anti-Histone demethylase JARID1B antibody,anti-Jumonji antibody,anti-ARID domaincontaining protein 1B antibody,anti-Retinoblastomabinding protein 2 homolog 1 antibody

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UniProt Details

No UniProt data available

Protocol Information

WB
Western Blot (IB, immunoblot)
View Protocol

Available Sizes

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100 μl
$ 440.00
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Free Secondary Antibody (20 ul)0/0

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DispatchUsually dispatched within 5-10 working days.
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