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KDM7 (M) Antibody, Rabbit Polyclonal

SKU: orb67002

Description

Rabbit polyclonal to KDM7.Lysine-specific histone demethylase 7 (KDM7) is a histone demethylase required for braindevelopment. KDM7 specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 andH3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue(H4K20Me1), thereby playing a central role in histone code. KDM7 specifically binds trimethylated'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3,it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2.

Research Area

Epigenetics

Images & Validation

Tested ApplicationsIP, WB
Dilution RangeWB:1:1000-1:5000
ReactivityHuman

Key Properties

HostRabbit
ClonalityPolyclonal
Immunogenmiddle region of human KDM7
Molecular Weight107
PurityAffinity purification
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives0.01% NaN3
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

anti-KDM7 antibody,anti-Lysinespecific demethylase 7 antibody,anti-JmjC domaincontaining histone demethylation protein 1D antibody,anti-JHDM1D antibody,anti- KIAA1718 antibody
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UniProt Details

No UniProt data available

Protocol Information

WB
Western Blot (IB, immunoblot)
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IP
Immunoprecipitation
View Protocol

Available Sizes

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100 μl
$ 440.00
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Free Secondary Antibody (20 ul)0/0

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DispatchUsually dispatched within 5-10 working days.
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