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KIRA9

SKU: orb1685990

Description

KIRA9 is a potent IRE1 inhibitor with an IC50 of 4.8 µM in INS-1 cells, acting by competitively occupying the ATP-binding site. This mechanism blocks ER-associated mRNA decay and apoptosis, making it a valuable tool for studying ER stress in models of diabetes and neurodegenerative disease.

Research Area

Cell Biology

Images & Validation

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KIRA9

Key Properties

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MW572.6
FormulaC27H27F3N6O3S
TargetOthers,IRE1,Apoptosis

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Quick Database Links

Gene Symbol
Others,IRE1,Apoptosis

Protocol Information

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Available Sizes

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25 mg
$ 1,560.00
50 mg
$ 2,020.00
100 mg
$ 2,540.00
DispatchUsually dispatched over 10 weeks
Bulk Enquiry
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Email

[email protected]

UK Office

+44 (0)1223 859353

US Office

+1 (415) 906-5211

CN Office

+86 (27)-87663101

Distributors

biorbyt.com/distributor