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KOR agonist 2

SKU: orb3134626

Description

KOR agonist 2 (Compound 23p) is an agonist of the κ opioid receptor (κopioid receptor, KOR) with a Ki of 1.9 nM. In murine models, KOR agonist 2 demonstrates analgesic effects with an ED50 of 1.30 mg/kg. It exhibits high clearance in mice when administered intravenously at 2 mg/kg and shows high metabolism and clearance in liver microsomes.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

FormulaC29H35ClN2O4S
TargetOpioid Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information