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LAS190792

SKU: orb1982696

Description

LAS190792 (AZD8999) is a dual-acting muscarinic antagonist and β2-adrenoceptor agonist with high receptor potency, particularly at M4 (pIC50 9.2) and β2 (pIC50 9.1). This pharmacological profile supports its investigation as a bronchodilator in respiratory disease research, including in vitro binding assays and in vivo models of airway constriction.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1347232-69-2
MW811.36
FormulaC39H43ClN4O9S2
SMILESCOc1cc(NC(=O)OCCN(C)[C@H]2CC[C@@H](CC2)OC(=O)C(O)(c2cccs2)c2cccs2)c(Cl)cc1CNC[C@H](O)c1ccc(O)c2[nH]c(=O)ccc12
TargetAdrenergic Receptor,Others,AChR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information