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Lepzacitinib

SKU: orb1944621

Description

Lepzacitinib is a selective, small molecule JAK1/3 inhibitor used for the treatment of atopic dermatitis and other skin diseases. As a Janus kinase inhibitor, it reduces the inflammatory response.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number2321488-47-3
MW355.39
Purity99.85%
FormulaC18H21N5O3
SMILESN(C1=C2C(=NC=C1C(OCC)=O)NC=C2)[C@H]3CN(C(CC#N)=O)CCC3
TargetJAK
SolubilityDMSO:80 mg/mL (225.1 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.29 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

ATI1777, ATI-1777

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Key Properties

No computed properties available.

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Lepzacitinib (orb1944621)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
¥ 1,170.00
5 mg
¥ 2,080.00
1 ml x 10 mM (in DMSO)
¥ 2,210.00
10 mg
¥ 2,990.00
25 mg
¥ 5,460.00
50 mg
¥ 7,930.00
100 mg
¥ 10,790.00
200 mg
¥ 15,080.00
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