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Leriglitazone

SKU: orb1989209

Description

Leriglitazone, a metabolite of pioglitazone, binds to the PPARγ C-terminal ligand-binding domain (Ki: 1.2 μM) and induces transcriptional efficacy of the PPARγ (EC50: 680 nM). Leriglitazone PioOH is a PPARγ agonist, stabilizes the PPARγ activation function-2 (AF-2) co-activator binding surface.

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Key Properties

CAS Number146062-44-4
MW372.44
FormulaC19H20N2O4S
SMILESO=C1SC(C(=O)N1)CC2=CC=C(OCCC3=NC=C(C=C3)C(O)C)C=C2
TargetPPAR,Others

Storage & Handling

Storage-20°C
DisclaimerFor research use only

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Leriglitazone (orb1989209)

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