Leronlimab Antibody

SKU: orb1980388

Description

Leronlimab (PRO 140) is a humanized IgG4 anti-CCR5 monoclonal antibody with both anti-HIV and anti-tumor activity, inhibiting CCR-mediated HIV-1 virus and cancer cell metastasis in mouse tumor models. Leronlimab can be used to study HIV, non-alcoholic steatohepatitis (NASH), and breast cancer.

Research Area

Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Images & Validation

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Key Properties

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Antibody Type	Inhibitor Antibody
Clonality	Monoclonal
Target	CCR,HIV Protease
Molecular Weight	146.66 kDa
Purity	95.00%
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Concentration	2.43 mg/mL
Disclaimer	For research use only

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Gene Symbol

CCR,HIV Protease

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