Cart summary

You have no items in your shopping cart.

LL-K8-22

SKU: orb1982623

Description

LL-K8-22 is a potent and selective dual degrader of CDK8-cyclin C, with DC50 values around 2.5 μM. It suppresses STAT1 S727 phosphorylation and inhibits oncogenic E2F/MYC transcriptional programs. This compound is a research tool for studying triple-negative breast cancer (TNBC) in both cellular and animal models.

Research Area

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

MW573.77
FormulaC37H43N5O
TargetOthers,STAT,CDK,Early 2 Factor (E2F)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

LL-K8-22 (orb1982623)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%