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Lorotomidate

SKU: orb3136076

Description

Lorotomidate (Example 16) is a GABAA receptor agonist with anesthetic properties, demonstrated by an ED50 of 2 mg/kg and an LD50 of 46.5 mg/kg in Kunming mice via intravenous injection. Lorotomidate does not inhibit corticosteroid secretion in animals, indicating a favorable safety profile.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2093287-60-4
MW262.28
FormulaC14H15FN2O2
SMILES[C@H](C)(N1C(C(OCC)=O)=C(F)N=C1)C2=CC=CC=C2
TargetGABA Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information