Lorukafusp alfa Biosimilar (GD2 Reference Antibody）

SKU: orb2703714

Description

Lorukafusp alfa (14.18 mAb; hu14.18-IL2) is an immunocytokine consisting of the humanized 14.18 anti-GD2 mAb linked to IL210. Lorukafusp alfa has activity mediated by activation of antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity via the binding of hu14.18-IL2 to GD2 on the tumor cell surface, followed by binding to Fc receptors on effector cells along with activation of NK and T cells via IL2 receptor binding. Lorukafusp alfa has anti-tumor activity.

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Key Properties

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Antibody Type	Biosimilar Antibody
Clonality	Monoclonal
Target	Lorukafusp alfa Biosimilar（Anti-GD2 Reference Antibody）
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Lorukafusp alfa Biosimilar（Anti-GD2 Reference Antibody）

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