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LRRK2/NUAK1/TYK2-IN-1

SKU: orb1744911

Description

LRRK2/NUAK1/TYK2-IN-1 is a potent multi-kinase inhibitor with IC50 values under 10 nM against LRRK2 (wild-type and G2019S mutant), TYK2, and NUAK1. It serves as a valuable chemical probe for investigating the pathophysiology of autoimmune disorders and Parkinson's disease in both cellular and animal models.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number2629192-96-5
MW392.34
FormulaC20H11F3N6
SMILESFC=1C=C2C=3C(NC(=NC2=CC1C=4C=CN=NC4)C5=C(F)C=CC=C5F)=CNN3
TargetLRRK2,Others,JAK,AMPK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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25 mg
$ 1,560.00
50 mg
$ 2,020.00
100 mg
$ 2,540.00
DispatchUsually dispatched within 6-8 weeks
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