LRRK2/NUAK1/TYK2-IN-1

SKU: orb1744911

Description

LRRK2/NUAK1/TYK2-IN-1 is a potent multi-kinase inhibitor with IC50 values under 10 nM against LRRK2 (wild-type and G2019S mutant), TYK2, and NUAK1. It serves as a valuable chemical probe for investigating the pathophysiology of autoimmune disorders and Parkinson's disease in both cellular and animal models.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

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Key Properties

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CAS Number	2629192-96-5
MW	392.34
Formula	C₂₀H₁₁F₃N₆
SMILES	FC=1C=C2C=3C(NC(=NC2=CC1C=4C=CN=NC4)C5=C(F)C=CC=C5F)=CNN3
Target	LRRK2,JAK,AMPK,Others

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

168006953 ↗

Key Properties

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No computed properties available.

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