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LXRB Antibody

SKU: orb2644250

Description

The liver X receptors, LXRA (NR1H3) and LXRB (NR1H2) form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements. LXRB can inhibit proliferation and induce apoptosis of cancer cells.

Images & Validation

Tested ApplicationsELISA
Dilution RangeELISA: order Ab without BSA for coating
ReactivityHuman
Application Notes
Optimal dilution of the LXRB antibody should be determined by the researcher.

Key Properties

Antibody TypePrimary Antibody
HostMouse
ClonalityMonoclonal
IsotypeMouse IgG2c, kappa
Clone No.LXRB/2731
ImmunogenRecombinant full-length human NR1H2/LXRB protein was used as the immunogen for the LXRB antibody.
PurificationProtein G affinity chromatography
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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LXRB Antibody

SDS-PAGE analysis of purified, BSA-free LXRB antibody (clone LXRB/2731) as confirmation of integrity and purity.

UniProt Details

No UniProt data available

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Protocol Information

ELISA
Enzyme-linked Immunosorbent Assay (EIA)
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LXRB Antibody (orb2644250)

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Available Sizes

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100 μg
¥ 9,750.00
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Free Secondary Antibody (20 ul)0/0

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