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LY3405105

SKU: orb1298388

Description

LY3405105 is a novel, potent, and selective inhibitor of cyclin-dependent kinase 7 (CDK7). This small molecule is used in biochemical and cellular research to investigate CDK7's roles in transcription and cell cycle progression, with studies demonstrating its activity in both in vitro assays and in vivo cancer models.

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number2326428-25-3
MW497.63
Purity98.01% (May vary between batches)
FormulaC26H39N7O3
SMILESC(C)(C)C1=C2N(C(NC3CCN(C(OC4CN(C(/C=C/CN(C)C)=O)CC4)=O)CC3)=CC(C)=N2)N=C1
TargetCDK
SolubilityDMSO:4.98 mg/mL (10.01 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

SNU-16, inhibit, LY 3405105, LY3405105, LY-3405105, MCF7, Inhibitor, HCC1806, HCT116, anticancer, 1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester, CDK7, CDK, Cyclin-dependent kinase, Cyclin dependent kinase

Similar Products

  • LY3405105 [orb1218355]

    >98% (HPLC)

    2326428-25-3

    497.64

    C26H39N7O3

    5 mg, 100 mg, 10 mg, 25 mg, 50 mg, 200 mg, 1 g, 2 mg, 500 mg
Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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1 mg
$ 90.00
5 mg
$ 140.00
10 mg
$ 200.00
25 mg
$ 340.00
50 mg
$ 520.00
100 mg
$ 720.00
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