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m-PEG8-Lys(Mal)-Val-Ala-PAB-Ph-CO-Dazostinag

SKU: orb2664133

Description

This compound is an antibody-drug conjugate (ADC) linker-payload featuring a maleimide group for antibody conjugation, a protease-cleavable Val-Ala dipeptide, and a PAB spacer that releases the cytotoxic Dazostinag agent. It is a key research tool for developing targeted cancer therapies and studying drug delivery mechanisms in both in vitro and in vivo experimental models.

Images & Validation

Key Properties

CAS Number2553413-13-9
MW1779.72
FormulaC74H98F2N14O27P2S2
SMILESF[C@H]1[C@H](N2C=3C(N=C2)=C(NC(=O)C4=C(CN(C(OCC5=CC=C(NC([C@@H](NC([C@@H](NC([C@H](CCCCN6C(=O)C=CC6=O)NC(CCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)C(C)C)=O)C)=O)C=C5)=O)C)C=CC=C4)N=CN3)O[C@]7([C@]1(OP(=O)(S)OC[C@]8(O[C@H]([C@](OP(=O)(S)OC7)([C@@H]8O)[H])N9C%10=C(C(F)=C9)C(=O)N=CN%10)[H])[H])[H]
TargetDrug-Linker Conjugates for ADC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information