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Marbofloxacin

SKU: orb1304519

Description

Marbofloxacin (Zeniquin) is a broad-spectrum fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, thereby blocking DNA replication. It is widely used in veterinary research for in vitro susceptibility testing and in vivo models of bacterial infections.

Research Area

Infectious Disease & Virology, Molecular Biology

Images & Validation

Key Properties

CAS Number115550-35-1
MW362.36
Purity99.84% (May vary between batches)
FormulaC17H19FN4O4
SMILESO=C1C=2C3=C(C(=C(F)C2)N4CCN(C)CC4)OCN(C)N3C=C1C(O)=O
TargetAntibacterial,Topoisomerase,Antibiotic
SolubilityDMSO:2.18 mg/mL (6.02 mM)

Bioactivity

In Vivo
Marbofloxacin treatment at the therapeutic dose does not eliminate M. hyopneumoniae, with 87.5 to 100% of the pigs still positive at the end of the assays, and is not effective in significantly reducing clinical signs. Nevertheless, Marbofloxacin treatment seems to decrease the lung lesion scores. Administration of Marbofloxacin at 6 mg/kg once daily for 7 days in a Staphylococcus aureus infection in tissue cages in ponies is not effective for the elimination of S. aureus infections from secluded sites.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

antimicrobial, Antibiotic, Bacterial, bacteria, Gram-negative, Gram-positive, fluoroquinolone, Marbocyl, Marbofloxacin, Marbofloxacine, Inhibitor, inhibit, Mycoplasma, Topo IV, Topo II, Zeniquin

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Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

Marbofloxacin (orb1304519)

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% DMSO +
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% Tween 80 +
%

Available Sizes

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100 mg
¥ 910.00
500 mg
¥ 1,040.00
1 g
¥ 1,170.00
DispatchUsually dispatched within 3-5 working days
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