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MCI-INI-3

SKU: orb1473094

Description

MCI-INI-3 is a potent, selective, competitive inhibitor of ALDH1A3 (Ki=0.55 uM), shows poor inhibitory effect on the structurally related isoform ALDH1A1 (>140-fold selectivity).MCI-INI-3 also displays on inhibition against six isoforms of ALDH (ALDH16A1, ALDH7A1, ALDH9A1, ALDH2, ALDH1B1, ALDH18A1).MCI-INI-3 demonstrates selective binding to ALDH1A3 in glioma stem cell lysates, inhibits ALDH activity and affects RA synthesis in cells.

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Key Properties

CAS Number1011366-31-6
MW373.36
Purity>98%
FormulaC21H15N3O4
SMILESC12=CC(C3=CC=CC=C3)=NN1C(C(OC)=O)=CC(C1=CC=C3OCOC3=C1)=N2

Storage & Handling

Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

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5 mg
$ 820.00
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