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mDPR-Val-Cit-PAB-MMAE TFA

SKU: orb2283415

Description

mDPR-Val-Cit-PAB-MMAE TFA is a cleavable drug-linker conjugate for constructing Antibody-Drug Conjugates (ADCs). It incorporates the potent antimitotic agent MMAE, which is released upon protease cleavage, enabling targeted cytotoxicity in both in vitro and in vivo cancer research models.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number2185872-76-6
MW1403.58
FormulaC67H101F3N12O17
SMILESC(C(O)=O)(F)(F)F.[C@H]([C@H](C(N[C@@H]([C@@H](O)C1=CC=CC=C1)C)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(OCC3=CC=C(NC([C@@H](NC([C@@H](NC([C@H](CN)N4C(=O)C=CC4=O)=O)[C@@H](C)C)=O)CCCNC(N)=O)=O)C=C3)=O)C)C(C)C)=O)[C@@H](C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
TargetDrug-Linker Conjugates for ADC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information

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1 mg
$ 390.00
DispatchUsually dispatched within 5-10 working days
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