Mefloquine hydrochloride

SKU: orb1310226

Description

Mefloquine hydrochloride is a quinoline-based antimalarial agent effective against Plasmodium falciparum. It is widely used in malaria research for both chemoprevention and treatment studies, serving as a critical tool in parasitology for in vitro assays and in vivo animal models of infection.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	51773-92-3
MW	414.77
Purity	99.99% (May vary between batches)
Formula	C₁₇H₁₇ClF₆N₂O
SMILES	[C@@H](O)([C@@H]1NCCCC1)c1cc(nc2c1cccc2C(F)(F)F)C(F)(F)F.Cl
Target	Parasite,Reactive Oxygen Species,ROS Kinase,Potassium Channel,Autophagy,SARS-CoV
Solubility	DMSO:35.71 mg/mL (86.1 mM);Ethanol:76 mg/mL (183.23 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.82 mM)

Bioactivity

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Target IC50	K+ channel:1 microM

Storage & Handling

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Storage	store under nitrogen \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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AMPK, anticancer, antimalarial, Autophagy, Inhibitor, Mefloquin, Mefloquin hydrochloride, Mefloquin Hydrochloride, Mefloquine, Mefloquine HCl, Mefloquine hydrochloride, Mefloquine Hydrochloride, ERK, KcsA, inhibit, JNK, Parasite, Reactive Oxygen Species, ReactiveOxygenSpecies, Potassium Channel, PotassiumChannel, ROS, SARSCoV, SARS coronavirus, SARS-CoV

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Compound Identifiers

PubChem CID

65329 ↗

Key Properties

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No computed properties available.

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