Menthol

SKU: orb1301551

Description

DL-Menthol is a synthetic or naturally derived compound from mint oils, known for its cooling flavor and local anesthetic properties. It is widely used in research as a TRPM8 channel agonist for studying thermosensation, pain, and inflammation in both in vitro and in vivo models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	1490-04-6
MW	156.26
Purity	99.84% (May vary between batches)
Formula	C₁₀H₂₀O
SMILES	CC(C)C1CCC(C)CC1O
Target	Calcium Channel
Solubility	DMSO:50 mg/mL (319.98 mM)

Bioactivity

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In Vivo

High levels of the major DL-Menthol metabolite, menthol-glucuronide, was observed in the urine of smokers of either menthol or non-menthol cigarettes. The fact that a significant inverse correlation was observed between the levels of urinary menthol-glucuronide and NNAL-N-glucuronide, a major detoxification metabolite of the tobacco carcinogen, NNK, suggests that menthol may be inhibiting the clearance of this important tobacco carcinogen.

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Calcium Channel, CalciumChannel, DL-Menthol, Menthol

Quality Guarantee

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Compound Identifiers

PubChem CID

1254 ↗

Key Properties

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No computed properties available.

Protocol Information

Find More Protocols

Applications:	IF, IHC-Fr, IHC-P
Predicted Reactivity:	Bovine, Equine, Mouse, Porcine, Rabbit, Sheep
Reactivity:	Human, Rat
Species/Host:	Rabbit
Clonality:	Polyclonal
Conjugation:	Unconjugated

Reactivity:	Human
Dynamic Range:	0.32-20 ng/mL
Sensitivity:	0.113 ng/mL

Reactivity:	Human
Dynamic Range:	0.31-20ng/mL
Sensitivity:	0.14ng/mL

Reactivity:	Human
Dynamic Range:	0.31-20ng/mL
Sensitivity:	0.14ng/mL

Applications:	IHC, IHC-P
Reactivity:	Canine, Guinea pig, Hamster, Human, Mammal, Monkey, Rabbit
Species/Host:	Rabbit
Clonality:	Polyclonal
Conjugation:	Unconjugated

Menthol

Description

Research Area

Images & Validation

Key Properties

Bioactivity

Storage & Handling

Alternative Names

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Key Properties

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