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Metoclopramide hydrochloride

SKU: orb1309870

Description

Metoclopramide hydrochloride is a dopamine D2 receptor antagonist employed as an antiemetic agent. It is widely used in research to investigate gastrointestinal motility and vomiting mechanisms, with applications in both in vitro receptor binding assays and in vivo animal models of emesis.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number7232-21-5
MW336.26
Purity99.94% (May vary between batches)
FormulaC14H22ClN3O2·HCl
SMILESCl.CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC
TargetAChR,5-HT Receptor,Dopamine Receptor
SolubilityDMSO:50 mg/mL (148.69 mM);H2O:61 mg/mL (181.41 mM);Ethanol:62 mg/mL (184.38 mM)

Bioactivity

Target IC50
D2 receptor:483 nM (IC50)|5-HT3 receptor:308 nM (IC50)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

DopamineReceptor, Dopamine Receptor, Dopamine, 5-hydroxytryptamine Receptor, 5HTReceptor, 5-HT, 5-HT Receptor, 5HT Receptor, gastro-oesophageal, gastroparesis, Maxolon, Inhibitor, inhibit, nausea, Metoclopramide, Metoclopramide HCl, Metoclopramide hydrochloride, Metoclopramide Hydrochloride, mAChR, vomiting, reflux, Serotonin Receptor

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 ml x 10 mM (in DMSO)
$ 80.00
10 mg
$ 80.00
25 mg
$ 90.00
50 mg
$ 120.00
100 mg
$ 140.00
200 mg
$ 190.00
500 mg
$ 290.00
DispatchUsually dispatched within 3-5 working days
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