Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

MI-883

SKU: orb2944451

Description

MI-883 is a dual-function small molecule acting as a Constitutive Androstane Receptor (CAR) agonist and a Pregnane X Receptor (PXR) antagonist. It modulates cytochrome P450 gene expression (CYP2B6, CYP3A4) in hepatic cell models and has demonstrated efficacy in improving hypercholesterolemia in mouse studies, making it a valuable tool for nuclear receptor and metabolic disease research.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number2530027-71-3
MW481.309
FormulaC23H15Cl2FN6O
SMILESO=C(N)C1=CC(=CC=C1Cl)CN2N=NC(=C2)C3=C(N=C4C=C(F)C=CN43)C=5C=CC(Cl)=CC5
TargetCytochromes P450

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information