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MI-883

SKU: orb2944451

Description

MI-883 is a dual-function small molecule acting as a Constitutive Androstane Receptor (CAR) agonist and a Pregnane X Receptor (PXR) antagonist. It modulates cytochrome P450 gene expression (CYP2B6, CYP3A4) in hepatic cell models and has demonstrated efficacy in improving hypercholesterolemia in mouse studies, making it a valuable tool for nuclear receptor and metabolic disease research.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number2530027-71-3
MW481.309
FormulaC23H15Cl2FN6O
SMILESO=C(N)C1=CC(=CC=C1Cl)CN2N=NC(=C2)C3=C(N=C4C=C(F)C=CN43)C=5C=CC(Cl)=CC5
TargetCytochromes P450

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

MI-883 (orb2944451)

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