Mizoribine 5'-monophosphate

SKU: orb3175144

Description

Mizoribine 5'-monophosphate is the active metabolite of Mizoribine. It acts as an inhibitor of inosine-5’-monophosphate dehydrogenase (IMPDH), with inhibition constants (Ki) of 3.3, 72, and 157 nM for Trypanosoma brucei, Bacillus subtilis, and marine Bacillus species IMPDH, respectively. Mizoribine 5'-monophosphate is utilized in antitrypanosomal and immunosuppressive research.

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Key Properties

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CAS Number	62025-48-3
MW	339.2
Formula	C₉H₁₄N₃O₉P
SMILES	OC=1N(C=NC1C(N)=O)[C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O
Target	Parasite,Dehydrogenase,Drug Metabolite

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Parasite,Dehydrogenase,Drug Metabolite

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