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MK-5046

SKU: orb1705166

Description

MK-5046 is a potent and selective bombesin receptor subtype-3 (BRS-3) agonist, exhibiting high binding affinity for both mouse (Ki=1.6 nM) and human (Ki=25 nM) receptors. This small molecule is a valuable research tool for investigating BRS-3 function in metabolic regulation and energy homeostasis through in vitro and in vivo studies.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1022152-70-0
MW444.37
Purity98.56% (May vary between batches)
FormulaC20H18F6N4O
SMILESO[C@@](Cc1nc(CC2(CC2)C(F)(F)F)c[nH]1)(c1ccc(cc1)-n1cccn1)C(F)(F)F
TargetBombesin Receptor
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.25 mM);DMSO:10 mM

Bioactivity

Target IC50
BRS3 (human):25 nM(ki)|BRS3 (mouse):1.6 nM (ki)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

BombesinReceptor, Bombesin Receptor, BRS-3, inhibit, MK5046, MK-5046, MK 5046, Inhibitor

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  • MK5046 [orb1227137]

    >98% (HPLC)

    1022152-70-0

    444.37

    C20H18F6N4O

    5 mg, 10 mg, 25 mg, 50 mg, 1 g, 100 mg, 200 mg, 500 mg
Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

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1 mg
$ 120.00
5 mg
$ 220.00
10 mg
$ 310.00
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