MLL5 (N) Antibody, Rabbit Polyclonal

SKU: orb66810

Description

Rabbit polyclonal to MLL5.MLL5 is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family. It is a histonemethyltransferase that specifically mono-and dimethylates Lys-4 of histone H3 (H3K4me1 andH3K4me2). Lys-4 methylation of H3 represents a specific tag for epigenetic transcriptional activation.It is a key regulator of hematopoiesis involved in terminal myeloid differentiation and in the regulationof hematopoietic stem cell self-renewal by a mechanism that involves DNA methylation.Overexpression of MLL5 inhibits cell cycle progression while knockdown induces cell cycle arrest atboth the G1 and G2/M phases.

Research Area

Stem Cells

Images & Validation

−

Item 1 of 1

Tested Applications	WB
Dilution range	WB:1:1000-1:5000
Reactivity	Human

Key Properties

−

Host	Rabbit
Clonality	Polyclonal
Immunogen	N-terminal region of human MLL5
Molecular Weight	205
Purity	Affinity purification
Conjugation	Unconjugated

Storage & Handling

−

Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives	0.01% NaN3
Disclaimer	For research use only

Alternative Names

−

anti-MLL5 antibody,anti-FLJ10078 antibody,anti-FLJ14026 antibody,anti-HDCMC04P antibody,anti-KMT2E antibody,anti-MGC70452 antibody

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Western blot analysis of total cell extracts from human Hela using MLL5 antibody

Quick Database Links

UniProt

Q8IZID2

UniProt Details

−

No UniProt data available

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Western Blot (IB, immunoblot)

View Protocol

Find More Protocols