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MMPSI

SKU: orb1704938

Description

MMPSI is a non-peptide, small-molecule inhibitor of caspase-3 and caspase-7. It demonstrates cardioprotective effects by reducing ischemic injury in ex vivo rabbit heart models and inhibiting apoptosis in cardiomyocyte cultures, making it a useful tool for studying myocardial injury and cell death pathways.

Research Area

Cell Biology, Protein Biochemistry

Images & Validation

Key Properties

CAS Number220509-74-0
MW324.35
Purity99.96% (May vary between batches)
FormulaC14H16N2O5S
SMILESO=C1C=2C(=CC=C(S(=O)(=O)N3[C@H](COC)CCC3)C2)NC1=O
TargetApoptosis,Caspase
SolubilityH2O:2 mg/mL (6.17 mM);DMSO:80 mg/mL (246.65 mM)

Bioactivity

Target IC50
Caspase-3 (human):1.7 μM

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Caspase 3/7 Inhibitor I, Caspase-3, Caspase3/7 Inhibitor I, Caspase-3/7 Inhibitor I, Caspase-7, Apoptosis
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Key Properties

No computed properties available.

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Protocol Information

MMPSI (orb1704938)

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% DMSO +
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% Tween 80 +
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Available Sizes

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1 mg
¥ 1,820.00
5 mg
¥ 4,810.00
10 mg
¥ 7,410.00
25 mg
¥ 13,390.00
50 mg
¥ 20,800.00
100 mg
¥ 31,980.00
DispatchUsually dispatched within 3-5 working days
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