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MMT3-72

SKU: orb2565770

Description

MMT3-72 is a selective JAK1 inhibitor demonstrating potent anti-inflammatory effects in preclinical models. It significantly reduces phospho-STAT3 levels and shows superior efficacy in ameliorating DSS-induced colitis in vivo, making it a valuable research tool for investigating JAK-STAT pathways in inflammatory bowel disease.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number2996158-39-3
MW810.87
FormulaC40H42N8O9S
SMILESO(CCOC1=CC=C(NC=2N=C(NC3=CC(S(NC(C)(C)C)(=O)=O)=CC=C3)C(C)=CN2)C=C1)C4=C(C(O)=O)C=C(/N=N/C5=CC=C(C(NCCC(O)=O)=O)C=C5)C=C4
TargetJAK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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MMT3-72 (orb2565770)

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