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MRC-G-001

SKU: orb3136059

Description

MRC-G-001 is a Genipin derivative with an IC50 value of 117 μM against A549 cancer cells. It inhibits the phosphorylation of EGFR, JAK1, and STAT3, and modulates the expression of proteins related to epithelial-mesenchymal transition (EMT), thereby suppressing cell migration and invasion. MRC-G-001 induces cell cycle arrest and apoptosis (apoptosis) and is applicable in studies of cancers, including non-small cell lung cancer.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

TargetApoptosis,STAT,JAK,EGFR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information