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N-Arachidonoyl glycine

SKU: orb1704323

Description

N-Arachidonylglycine (NA-Gly) is a thermogenic circulating lipid metabolite exhibiting anti-inflammatory, anticancer, antidiabetic, and antioxidant properties. It serves as a valuable research tool for investigating metabolic and inflammatory pathways in both in vitro and in vivo experimental models.

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number179113-91-8
MW361.53
Purity>98%
FormulaC22H35NO3
SMILESCCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCC(O)=O
TargetGPCR
SolubilitySoluble in DMSO (up to 50 mg/ml).

Bioactivity

Target IC50
GlyT2:5.1 μM
In Vivo
In rats, oral administration of N-arachidonylglycine (10 mg/kg) inhibits FAAH, leading to a reduction in the hydrolytic degradation of anandamide.
In Vitro
In HEK293-GPR18 cells, N-arachidonoylglycine (0.1 nM - 100 µM; 5 minutes) promotes MAPK activation.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

NA-Gly
Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

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5 mg
$ 160.00
25 mg
$ 300.00
DispatchUsually dispatched within 5-10 working days
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