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Naltrindole 5′-isothiocyanate

SKU: orb2944589

Description

Naltrindole 5′-isothiocyanate (5'-NTII) is an irreversible antagonist selective for the delta opioid receptor (δ-OR). It effectively blocks analgesia from the agonist DSLET while sparing effects from DPDPE, making it a key tool for studying δ-OR subtypes in both in vitro binding assays and in vivo pain modulation research.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number126876-64-0
MW471.571
FormulaC27H25N3O3S
SMILESO[C@]12[C@@]34C=5C(O[C@]3(C6=C(C1)C=7C(N6)=CC=C(N=C=S)C7)[H])=C(O)C=CC5C[C@]2(N(CC8CC8)CC4)[H]
TargetOpioid Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Naltrindole 5′-isothiocyanate (orb2944589)

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