Narnatumab Antibody

SKU: orb2803555

Description

Narnatumab (IMC-RON8) is a humanized monoclonal antibody designed to target the RON (MST1R) receptor, exhibiting antitumor activity. It is utilized in preclinical and clinical research for advanced solid tumors, with studies investigating its effects in both in vitro cellular assays and in vivo xenograft models.

Research Area

Signal Transduction

Images & Validation

−

Key Properties

−

CAS Number	1188275-92-4
MW	145.8 kDa
Purity	99.57% (SEC-HPLC)
Target	c-Met/HGFR

Bioactivity

−

Target IC50	RON:32 pM (Kd)
In Vitro	Narnatumab is a fully humanized monoclonal antibody that binds to RON with high affinity and subsequently prevents RON from binding to HGFL.

Storage & Handling

−

Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

−

LY 3012219, LY3012219, IMC-RON-8, IMCRON8, IMC-RON8, Anti-MSPR/RON/CD136 Reference Antibody

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Quick Database Links

Gene Symbol

c-Met/HGFR

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols