NCOA1 (N) Antibody, Rabbit Polyclonal

SKU: orb66875

Description

Rabbit polyclonal to NCOA1.NCOA1 is a nuclear receptor coactivator that directly binds nuclear receptors and stimulates thetranscriptional activities in a hormone-dependent fashion. NCOA1 is involved in the coactivation ofvarious nuclear receptors, such as for steroids (PGR, GR and ER), retinoids XRs), thyroid hormone(TRs) and prostanoids (PPARs). NCOA1 is also involved in coactivation mediated by STAT3,STAT5A, STAT5B and STAT6 transcription factors. NCOA1 displays histone acetyltransferase activitytoward H3 and H4, and plays a central role in creating multisubunit coactivator complexes that act byboth chromatin remodeling and recruient of general transcription factors.

Research Area

Cancer, Epigenetics

Images & Validation

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Item 1 of 1

Tested Applications	WB
Dilution range	WB:1:1000-1:5000
Reactivity	Human

Key Properties

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Host	Rabbit
Clonality	Polyclonal
Immunogen	N-terminal region of human NCOA1
Molecular Weight	157
Purity	Affinity purification
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives	0.01% NaN3
Disclaimer	For research use only

Alternative Names

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anti-NCOA1 antibody,anti-Nuclear receptor coactivator 1 antibody,anti-NCoA1 antibody,anti-Class E basic helixloophelix protein 74 antibody,anti-bHLHe74 antibody,anti-Protein Hin2 antibody,anti-RIP160 antibody,anti-Renal carcinoma antigen NYREN52 antibody,anti-Steroid receptor coactivator 1 antibody,anti-SRC1 antibody,anti- BHLHE74 antibody,anti-SRC1 antibody

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Western blot analysis of total cell extracts from human 293T using NCOA1 antibody

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UniProt

Q15788

UniProt Details

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No UniProt data available

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Protocol Information

Western Blot (IB, immunoblot)

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