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Necroptosis-IN-1

SKU: orb1298199

Description

Necroptosis-IN-1 is a potent, small-molecule inhibitor of RIPK1, functioning as a necroptosis inhibitor and an analog of Necrostatin-1. It is widely used in biochemical and cellular research to study programmed necrosis pathways in both in vitro and in vivo experimental models.

Research Area

Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number1391980-92-9
MW263.68
Purity99.73% (May vary between batches)
FormulaC12H10ClN3O2
SMILESClc1cccc2c(CC3NC(=O)NC3=O)c[nH]c12
TargetRIP kinase
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (18.96 mM);DMSO:249 mg/mL (944.33 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, Inhibitor, Necroptosis, Necroptosis IN 1, NecroptosisIN1, Necroptosis-IN-1, Receptor-interacting protein kinases, RIPK, RIPK1, RIPkinase, RIP kinase

Similar Products

  • Necroptosis-IN-1 [orb1218862]

    >98% (HPLC)

    1391980-92-9

    263.68

    C12H10ClN3O2

    5 mg, 10 mg, 25 mg, 50 mg, 2 mg, 100 mg, 500 mg, 1 g
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 100.00
5 mg
$ 160.00
1 ml x 10 mM (in DMSO)
$ 200.00
10 mg
$ 240.00
25 mg
$ 380.00
50 mg
$ 520.00
100 mg
$ 720.00
200 mg
$ 930.00
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