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Neoseptin-3

SKU: orb3029186

Description

Neoseptin-3 is a novel small molecule agonist that selectively activates the mouse TLR4/MD-2 complex with an EC50 of 18.5 µM, while exhibiting no activity on the human ortholog. This species-specific tool compound is valuable for in vitro and in vivo research applications in murine models of innate immunity and inflammation.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number1622863-21-1
MW474.59
FormulaC29H34N2O4
SMILESC(N[C@@H](CCC1=CC=CC=C1)C(OC(C)(C)C)=O)(=O)C2=CC(CCC3=CC=C(O)C=C3)=C(N)C=C2
TargetTLR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

Neoseptin-3 (orb3029186)

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