Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

Neptinib

SKU: orb2663624

Description

Neptinib (NEP010) is an orally bioavailable afatinib derivative with potent antitumor activity. It strongly inhibits wild-type and mutant EGFR kinases, including L858R and T790M variants, and demonstrates significant suppression of tumor growth in NSCLC mouse models. This makes it a valuable tool for in vitro and in vivo oncology research targeting EGFR-driven cancers.

Research Area

Cardiovascular Research, Signal Transduction

Images & Validation

Key Properties

CAS Number2085843-51-0
MW443.90
FormulaC22H23ClFN5O2
SMILESN(C=1C2=C(C=C(OCC)C(NC(/C=C/CN(C)C)=O)=C2)N=CN1)C3=CC(Cl)=C(F)C=C3
TargetEGFR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information