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Neuroprotective agent 15

SKU: orb3173601

Description

Neuroprotective agent 15 (Compound 3e) acts as a neuroprotective agent that selectively inhibits butyrylcholinesterase (BChE), with IC50 values of 2.6 μM for BChE and 114.3 μM for acetylcholinesterase (AChE). It also functions as a cannabinoid CB2 receptor agonist. This compound reduces cell death, decreases LDH release and Caspase-3/7 activity, thereby inhibiting apoptosis. Additionally, it reduces superoxide radical formation, maintains cellular morphology, and lowers oxidative stress levels. Neuroprotective agent 15 is useful in studies of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.

Images & Validation

Key Properties

CAS Number2476614-40-9
MW364.45
FormulaC20H24N6O
SMILESOC1=CC=C(C=C1)CN2C=NC=3C2=NC(=NC3N4CCCC4)N5CCCC5
TargetCaspase,Cannabinoid Receptor,Dehydrogenase,Cholinesterase (ChE),Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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