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Nirmatrelvir

SKU: orb1940233

Description

PF-07321332 is a potent and orally active inhibitor of SARS-CoV 3C-like protease (3CLPRO) .(In Vitro):PF-07321332 is a promising oral antiviral clinical candidate with well-established anti-SARS-CoV-2 activity in vitro.(In Vitro):3CLPRO is responsible for cleaving polyproteins 1a and 1ab of SARS-CoV-2.1. Without the activity of the SARS-CoV-2 3CLPRO, nonstructural proteins (including proteases) cannot be released to perform their functions, inhibiting viral replication.

Images & Validation

Key Properties

CAS Number2628280-40-8
MW499.53
Purity>98% (HPLC)
FormulaC23H32F3N5O4
SMILESCC(C)(C)[C@@H](C(N(C[C@@H]1C(C)(C)[C@H]11)[C@@H]1C(N[C@@H](C[C@H](CCN1)C1=O)C#N)=O)=O)NC(C(F)(F)F)=O
SolubilityIn Vitro: DMSO : 140 mg/mL (280.26 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

PF-07321332

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Nirmatrelvir (orb1940233)

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% DMSO +
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% Tween 80 +
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Available Sizes

Select a size below

2 mg
¥ 1,560.00
5 mg
¥ 2,340.00
10 mg
¥ 3,380.00
25 mg
¥ 5,720.00
50 mg
¥ 8,580.00
100 mg
¥ 10,920.00
200 mg
¥ 15,340.00
500 mg
¥ 22,880.00