(+)-Norfenfluramine

SKU: orb3027120

Description

(+)-Norfenfluramine, the principal hepatic metabolite of (+)-fenfluramine, acts as a selective agonist for the 5-HT2B receptor, exhibiting a potent K i of 11.2 nM. It significantly promotes the hydrolysis of inositol phosphates and heightens intracellular Ca2+ levels. This compound is valuable in the study of primary pulmonary hypertension and valvular heart disease.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	19036-73-8
MW	203.2
Formula	C₁₀H₁₂F₃N
SMILES	C[C@H](N)Cc1cccc(c1)C(F)(F)F
Target	5-HT Receptor

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

5-HT Receptor

Protocol Information

Find More Protocols

CAS Number:	37936-89-3
MW:	239.67
Formula:	C₁₀H₁₃ClF₃N

CAS Number:	673-18-7
MW:	239.67
Formula:	C₁₀H₁₃ClF₃N